Studies on the Quality Standard of Huoxiang Zhengqi Capsules
- VernacularTitle:藿香正气胶囊的质量标准研究
- Author:
Xueping WENG
;
Huimin LI
- Publication Type:Journal Article
- Keywords:
Huoxiang Zhengqi Capsules;
TLC;
Magnolol;
Honokiol;
HPLC;
Content derermiantion
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
1993;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To establish a method for the quality control of Huox ia ng Zhengqi Capsules(HZC). Methods Radix Angelicae Dahuricae, Herba Pogostemo nis, Pericarpium Citri Reticulatae and Rhizoma Atractylodis Macrocephalae in HZ C were identified by TLC. The content of magnolol and honokiol were determined b y HPLC. The chromatographic conditions were: Diamonsil C18 (250 mm? 4.6 mm, 5 ? m) column, mobile phase being methanol- acetonitrile- water (20 ∶ 15 ∶ 9 ), and the detection wavelength at 294 nm.Results The qualitative identificat ion with TLC was specific. The linear ranges of magnolol and honokiol were 16.14 4~ 80.72 ? g/mL (r=0.9998) and 20.48~ 102.40 ? g/mL( r=0.9997) , the avera ge recovery were 97.07 % and 97.89 % and RSD were 1.17 % and 1.06 % resp ectively. Conclusion This method is sensitive, stable and accurate. It can be used for the quality control of HZC.