Supercritical CO_2 Fluid Extraction of Tetrahydropalmatine from Corydalis yanhusuo W.T.Wang by Orthogonal Design
- VernacularTitle:超临界CO_2流体萃取延胡索中延胡索乙素的正交试验研究
- Author:
Feng CHEN
;
Liwei GUO
;
Shanlin JING
;
Daizhu WANG
- Publication Type:Journal Article
- Keywords:
Corydalis yanhusuo W.T.Wang;
SFE- CO2;
Orthogonal design;
Tetra hydropalmatine;
HPLC
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
1993;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To find out the optimal supercritical CO2 fluid extr ac tion prosess for Tetrahydropalmatine. Methods The extraction process was optimiz ed by orthogonal design with the yield of Tetrahydropalmatine as markers. Three factors including extraction pressure, temperature and the volume of entrainer were observed. Results The optimal condition of supercritical CO2 fluid extrac tion process was: under the pressure of 15Mpa at 40 ℃ , 1.5 fold of 95 % EtO H with Corydalis yanhusuo W.T.Wang as the entrainer. Conclusion The optimal supe rcritical process is feasible, with the advantage of low temperature and energy consumption, short time, high production and no organic residua.
