The level and clinical significance of laminin and hyaluronic acid in the cerebrospinal fluid of patients with neuropsychiatric lupus
- VernacularTitle:神经精神狼疮患者脑脊液层粘蛋白透明质酸测定的临床意义
- Author:
Lian YU
;
Longtian CHEN
;
Lizhen YU
;
Yumin LI
- Publication Type:Journal Article
- Keywords:
Lupus vasculitis, central nervous system;
Cerebrospinal fluid;
Laminin;
Hyaluronic acid
- From:
Chinese Journal of Rheumatology
2001;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the level and clinical significance of laminin (LN) and hyalu-ronic acid (HA) in cerebrospinal fluid (CSF) of patients with neuropsychiatric lupus (NPLE). Methods The level of LN and HA in CSF in 31 cases of NPLE, 36 cases of no-NPLE SLE, 23 cases of no-SLE cerebrovascular disease and 39 normal controls were messured by radioimmunoassay method. Results The level of LN and HA in CSF of NPLE patients was higher than that of the no-NPLE, no-SLE cerebrovascular disease and normal controls (P