Investigation of orthogonal design of supercritical fluid extraction(SFE) for extracting anthraquinone aglycones from Rhubarb
- VernacularTitle:正交实验法优化大黄蒽醌超临界流体萃取的研究
- Author:
Yumin LIU
;
Minjun CHEN
;
Xiaoku HONG
- Publication Type:Journal Article
- Keywords:
orthogonal design;
anthraquinone aglycones;
SFE
- From:
Chinese Traditional Patent Medicine
1992;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To optimize the extraction of the anthraquinone aglycnes from Rhubarb using supercritical fluid extraction(SFE). METHODS: Orthogonal design and variance analysis were used to optimize five operational variables of SFE. RESULTS: The optimized operational variables of SFE were obtained as following: the temperature was 70 ?C , the pressure was 35 MPa, the static extraction time was 8 min, the dynamic extraction volume 5 mL and methanol were used as modifier. CONCLUSION: SFE is rapid, convenient and accurate, and can be used to extract athraquinone aglycones from Rhubarb.
