Cardiovascular Management for the Prevention of Insult on the Central Nervous System in Prematurity.
- Author:
Jin Hee OH
1
Author Information
1. Department of Pediatrics, College of Medicine, The Catholic University of Korea, Seoul, Korea. Jeany@catholic.ac.kr
- Publication Type:Original Article
- Keywords:
Cardiovascular;
Prevention;
Central nervous system;
Prematurity
- MeSH:
Anoxia;
Blood Pressure;
Causality;
Central Nervous System*;
Ductus Arteriosus, Patent;
Hemorrhage;
Humans;
Hypotension;
Infant;
Infant, Newborn;
Infant, Premature;
Leukomalacia, Periventricular;
Reperfusion Injury
- From:Journal of the Korean Pediatric Cardiology Society
2007;11(3):161-168
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
High risk premature babies with various health problems needs long term follow up on the neurological impairment. The major neuropathologic lesions associated with premature babies are intraventricular hemorrhage and periventricular leukomalacia. Predisposing factors of these are prematurity itself, hypoxic-ischemic or hypotensive injury and reperfusion injury etc. For these, tenacious care of the infants fluid and electrolyte management including avoiding hypoxia, hypocarbia, hypotension, or wide fluctuation in neonatal blood pressure are important factors. In recent years there has been a growing debate whether patent ductus arteriosus (PDA) in prematurity treated or not during the neonatal life. Early treatment of PDA runs the risk of exposing infants to drugs or procedures they might not to be. In this review I am going to summary of the current debates on the treatment strategies of PDA in preterm infants in the aspect of cardiovascular management and present other strategies for the prevention of insult on the central nervous system in premature babies.
