Evaluation of emergency craniotomy for the treatment of patients with intracranial metastases of choriocarcinoma
- VernacularTitle:绒毛膜癌脑转移急诊行开颅手术的临床分析
- Author:
Juanjun YANG
;
Yang XIANG
;
Xiuyu YANG
;
Xirun WAN
;
Renzhi WANG
;
Zuyuan REN
;
Hongmei YIN
;
Weidong GUO
;
Xiaomu OU
- Publication Type:Journal Article
- Keywords:
Choriocarcinoma;
Brain neoplasms;
Neoplasm metastasis;
Surgical procedures, operative
- From:
Chinese Journal of Obstetrics and Gynecology
2001;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the diagnosis, management and prognosis of intracranial metastases of gestational trophoblastic tumour (GTT) patients who had emergency surgical decompression due to highly increased intracranial pressure. Methods Ninety-three patients with intracranial metastases of gestational trophoblastic tumour were hospitalized in our department of Peking Union Medical College Hospital from 1985 to 2004. Thirteen of them who underwent emergency craniotomy were retrospectively analyzed, and all of them presented with raised intracranial pressure and intracerebral haemorrhagic mass. Result Of the thirteen patients who underwent surgery in combination with multiagent systemic chemotherapy, seven achieved complete remission(CR), five had partial remission(PR), and one died of disease progression. Conclusions Emergency surgical treatment is the important method of choice for brain metastasis in patients displaying rapidly deteriorating signs. An undetermined intracranial haemorrhage in young female patients of reproductive age group should raise the suspicion of cerebral metastatic choriocarcinoma.
