Isolation and purification of neohesperidin reference substance from Fructus Aurantii
- VernacularTitle:从枳壳中分离纯化新橙皮苷对照品
- Author:
Yongxing XU
;
Haibin QU
;
Yiyu CHENG
- Publication Type:Journal Article
- Keywords:
Fructus Aurantii;
neohesperidin;
isolation;
purification
- From:
Chinese Traditional and Herbal Drugs
1994;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To isolate and purify high-purity neohesperidin from Fructus Aurantii extract.Methods Fructus Aurantii extract was treated by macroporous resin and extracted by n-butanol, then concentrated and some solid was precipitated.After crystallizing the precipitate three times, neohesperidin was obtained.The concentration of n-butanol extract was optimized, which was of great importance in the whole preparation.Results The yield of neohesperidin was 48.6% and purity of neohesperidin was up to 98.7% in Fructus Aurantii extract.Conclusion High-purity neohesperidin could be prepared feasibly and economically by proposed method.
