The value of procalcitonin in the diagnosis and prognosis of stoke-associated pneumonia

VernacularTitle:降钙素原在卒中相关性肺炎诊断和预后中的作用
Author: Hao ZHU ; Jijun XU ; Jun HU ; Yingshuo WANG
Publication Type:Journal Article
Keywords: diagnosis; prognosis; stoke-associated pneumonia; procalcitonin
From: Chongqing Medicine 2013;(31):3738-3739,3743
CountryChina
Language:Chinese
Abstract: Objective To observe the value of procalcitonin (PCT ) in the diagnosis ,treatment and prognosis judgement of stoke-associated pneumonia(SAP) .Methods The serum procalcitonin ,hs-CRP and clinical pulmonary infection scores (CPSI) of two groups were detected :SAP group(including 27 patients of stoke-associated pneumonia) and control group(including 31 healthy ob-jects) .Results The CPSI ,hs-CRP and serum concentration of PCT in SAP group were significantly higher than control group (P<0 .01) ,and decreased significantly when get better after treatment .The serum concentration of PCT in SAP group was significantly higher than control group(P<0 .01) .In SAP group ,the serum concentration of PTC was positively associated with CPSI scorers . Moreover ,the results of ROC analysis showed that the cut-off of serum procalcitonin for the diagnosis of SAP was 0 .9 ng/mL .The sensitivety was 88 .6% and the specifity was 79 .3% ,which was superior to hs-CRP .Conclusion The serum concentration of PCT in SAP patients is higher and it is associated with the prognosis .It might be a better clinical marker for the diagnosis and prognosis of SAP .