THE CHANGES OF THE TOTAL CHOLESTEROL,HIGH DENSITY LIPOPROTEIN, OXIDIZED LOW DENSITY LIPOPROTEIN, NITRIC MONOXIDE AND LIPOPEROXIDE IN SERUM AFTER THE ARCUATE NUCLEUS LESIONED
- VernacularTitle:毁损弓状核后血清中不同成分及一氧化氮和脂质过氧化物的变化
- Author:
Kaiyun WU
- Publication Type:Journal Article
- Keywords:
Arcuate nucleus;
Atherosclerosis;
Total cholesterol;
High density lipoprotein;
Oxidized low density lipoprotein;
Nitric monoxide;
lipoperoxide;
Rat
- From:
Acta Anatomica Sinica
1954;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the influence of the hypothalamic arcuate nucleus on the development of atherosclerosis. Methods The changes of the total cholesterol, high density lipoprotein, oxidized low density lipoprotein, nitric monoxide and lipoperoxide in serum were investigated after the arcuate nucleus lesioned with monosodium glutamate. Results The rat with arcuate nucleus lesioned had significant higher levels of total cholesterol, oxidized low density lipoprotein and lipoperoxide in serum than that of control subjects, but the level of nitric monoxide was lower and the high density lipoprotein in serum had no change.Conclusion This study indicated that hypothalamic arcuate nucleus might exert regulative effect in the development of atherosclerosis.
