Comparison of different methods for evaluating the similarity of the fingerprints of traditional Chinese medicines
- VernacularTitle:中药指纹图谱相似度评价方法的比较
- Author:
Lei NIE
;
Jin CAO
;
Guoan LUO
;
Yimin WANG
- Publication Type:Journal Article
- Keywords:
fingerprints of traditional Chinese medicines;
comparison method;
similarity assessment;
Tongbiding Injection;
mathematical statistics
- From:
Chinese Traditional Patent Medicine
1992;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: In this context, the high performance liquid chromatography (HPLC) of Tongbiding Injection was used as fingerprint examples of traditional Chinese medicine to compare the different methods for evaluating the similarity. METHODS: Computing methods for similarity assessments were first compared on the basis of theoretical analysis, and then comprehensive evaluations for performances of each method of similarity assessment were investigated via data simulation and statistics. RESULTS: The results manifested that each approach had its individual properties and limitations. Distance coefficient has better general properties as compared with other methods of assessing similarity. CONCLUSION: In practie, to estimate the similarity between the fingerprints of traditional Chinese medicines, the appropriate methods would be selected for the different problems, and therefore quality of traditional Chinese medicines would be better controlled.
