Studies on In-Vitro Biological Activity of Albiflorin R1 in Counteracting Cell Proliferation
- VernacularTitle:白芍苷R1体外抗细胞增殖活性初步研究
- Author:
Wenjun WANG
;
Peixun WANG
;
Ruiyan LIANG
- Publication Type:Journal Article
- Keywords:
ALBIFLORIN/phaimacology;
CELL CULTURE;
DRUG SCREENING ASSAYS, ANTITUMOR
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
2001;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
[Objective] To study the in-vitro biological activity of albiflorin R1 (AR1), a new monoterpene glycoside from Paeonia lactiflora,in counteracting cell proliferation. [Methods] Two kinds of human cancer cell strains (HeLa cells and K562 cells) and J774 macrophage cell strain were cultured in vitro to observe the effects of albiflorin Rl on cell proliferation. [Results] Albiflorin Rl could markedly inhibit the proliferation of J774 macrophages and also inhibit the proliferation of HeLa and K562 cell stains in vitro. [Conclusion] Albiflorin Rl may have an anti-neoplastic, anti-inflammatory and immunosuppressive activity.
