Determination of Thiamazole Content in Yingqi Ling Tablets by HPLC
- VernacularTitle:高效液相色谱法测定瘿气灵片中甲巯咪唑的含量
- Author:
Yiqun SUN
;
Yuechun HUANG
;
Hongmei TANG
- Publication Type:Journal Article
- Keywords:
YINGQI LING TABLETS/chemistry;
THIAMAZOLE/analysis;
CHROMATOGRAPHY, HIGH PRESSURE LIQUID
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
2001;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
[Objective] To develop a method for the determination of thiamazole content in Yingqi Ling Tablets. [Methods] High performance liquid chromatography (HPLC) was used. The chromatographic conditions were: C18 Gravity Column (4.6mm ? 250mm), methanol - water (10:90 ) as mobile phase, flow rate being 1.0mL/min and the detection wavelength at 258nm. [Results] The calibration curve was linear in the range of 0.16 - 0.64?g. The average recovery was 101.01% (relative standard deviation sr = 2.21%). Relative standard deviation of precision test was 1.04% and the content of the sample was 0.4841 mg per tablet (sR = 0.78%). [ Conclusion] HPLC is effective for the determination of thiamazole content in Yingqi Ling Tablets.
