Effects of Yifuning Soft Gelatin Capsules on Immune Function of Ovariectomized Rats
- VernacularTitle:益妇宁软胶囊对去势大鼠免疫功能的影响
- Author:
Wei XIAO
;
Yun MA
;
Hongzhu DENG
;
Lianbo WEI
- Publication Type:Journal Article
- Keywords:
Yifuning soft gelatin capsules;
Climacteric Syndrome;
Interleukin-2;
Estrogen receptor
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
1993;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of Yifuning soft gelatin capsules(YSGC)on immune function in ovariectomized (OVX) rats.Methods Fifty female mature Sprague-Dawley rats were randomized into 5 groups:normal control, model control, diethylstilbestrol tablets(DT)and YSGC(high-and low-dose). After 4-week treatment,the serum E2 and IL-2 levels were detected by radioimmunoassay. The estrogen receptor(ER)level in spleen were detected with method of radioligand receptor assay(RRA).The pathologic changes of thymus were observed under light microscope and the body weight,thymus index and spleen index were detected too.Results YSGC could obviously increase the serum levels of E2 and IL-2,increase spleen index and ER content in the spleen of OVX rats (P
