Effect of Shuluo Injection on Cerebral Ischemia-reperfusion in Mice
- VernacularTitle:舒络粉针对小鼠脑缺血再灌注的影响
- Author:
Jie CHEN
;
Dongping YUAN
;
Taihui FANG
- Publication Type:Journal Article
- Keywords:
Shuluo Injection;
Ischemia-reperfusion;
Cerebral water volume;
Cerebral index;
LDH;
NOS;
SOD
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
1993;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of Shuluo Injection on cerebral water volume,cerebral index ,LDH,NOS and SOD in the brain.Methods The model of cerebral ischemia-reperfusion in mice is set up by separating the bilateral common carotid artery (CCA) of the mice,blocking the blood stream by straining the thread and by reperfusion loosing the thread. After 3 times of ischemia-reperfusion,brain samples were prepared to observe the cerebral injury. Results High-dose Shuluo Injection significantly reduced the cerebral water volume and decreased the cerebral index and the activity of LDH and NOS(P
