Effect of Danshen Yin on Gastric Mucosal Defensive Factors in rats with Gastric Ulcer
- VernacularTitle:丹参饮对胃溃疡大鼠部分粘膜防御因子的影响
- Author:
Li LIU
;
Hongquan ZHANG
- Publication Type:Journal Article
- Keywords:
Danshen Yin;
Gastric ulcer;
Disease models,animal
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
1993;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of Danshen Yin on some gastric mucosal defensive factors in rats with acetic acid-induced gastric ulcer and to explore its anti-ulcer mechanisms.Methods Rat models with acetic acid-induced gastric ulcer were treated with Danshen Yin,ranitidine,and saline respectively for 14 days. After treatment,the ulcer index,serum nitric oxide(NO) level,plasma prostaglandin E2(PGE2)content and the number of micrangium in the granulation at the ulcer base were examined.Results The ulcer index in Dandhen Yin group and ranitidine group was significantly less than that in model group(P