Application of BODIPY for tooth whitening as a photosensitive drug

VernacularTitle:BODIPY光敏药物在牙齿美白上的应用研究
Author: Li LU ; Yanli CUI ; Tianjun LIU
Publication Type:Journal Article
Keywords: Photosensitive drug; Photodynamic therapy; Tooth whitening; Tooth remineralization
From: International Journal of Biomedical Engineering 2013;36(5):274-276,285,后插2
CountryChina
Language:Chinese
Abstract: Objective To study the tooth whitening effect of boron-dipyrromethene (BODIPY) as a photosensitive drug combining photodynamic therapy (PDT) and the influence on the surface of the enamel.Methods After oxidation of hydrogen peroxide or BODIPY by photodynamic therapy,the extracted teeth were evaluated by Vita shade guides matching.The change of surface enamel on the crystals and microstructure was observed by scanning electron microscopy (SEM).Results The teeth treated with BODIPY by PDT were smooth and whitened with the remineralization of teeth surface in morphology.While the teeth treated with hydrogen peroxide were whitened obviously but the surface morphology of the teeth was demineralized seriously.Conclusion The results suggest that PDT is effective for teeth whitening and can promote the remineralization of teeth surface enamel with BODIPY as a photosensitive drug.PDT is expected to become a new method for tooth whitening.