The proliferation of lymphocyte with stimulation of PPD after immunization with H37Ra in mice
- VernacularTitle:结核菌H37Ra免疫小鼠后PPD刺激淋巴细胞增殖转化的探讨
- Author:
Kun TAO
- Publication Type:Journal Article
- Keywords:
H37Ra;
Lymphocyte proliferation;
Mycobacterium tuberculosis;
PPD
- From:
Journal of Chongqing Medical University
1987;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To research the proliferation of lymphocyte with stimulation of purified protein derivative (PPD) after immunization with H37Ra in mice.Methods:The rate of lymphocyte proliferation with stimulation of PPD was determined at day 30 and day 60 after subcutaneous immunization and celiac immunization with H37Ra in mice.Results:After immunization with H37Ra in mice,the rate of lymphocyte proliferation by celiac immunization route and subcutaneous immunization route was 21.98% and 24.85% respectively at day 30;and it was 25.50% and 25.02% respectively at day 60.The rate of lymphocyte proliferation immunized with H37Ra at day 30 and day 60 were much higher than that of non-immunization( P 0.05);there were no significant difference between subcutaneous immunization route and celiac immunization route of H37Ra in mice.Conclusion:H37Ra can induce anti-tuberculosis immune response.
