Effect of compatibility with warming-inside drugs on paeoniflorin in mouse plasma
- VernacularTitle:温里药配伍对口服赤芍小鼠血浆中芍药苷的影响
- Author:
Zuyi YANG
;
Jin PEI
;
Rongmin LIU
;
Jia CHENG
;
Deguang WAN
;
Rong HU
- Publication Type:Journal Article
- Keywords:
Radix Paeoniae Rubra (RPR );
paeoniflroin;
warming-inside drugs (WID);
blood concentration: HPLC
- From:
Chinese Traditional and Herbal Drugs
1994;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To establish a RP-HPLC method for the determination of the blood concentration of paeoniflorin which was produced by seven kinds of warming-inside drugs (WID) being used with the promoting-blood drugs (PBD) individually and to explore the mechanism of PBD and WID compound prescription. Methods The blood concentration of peaoniflorin in mouse plasma was determined by HPLC after ig seven kinds of WID being compatible with Radix Paeoniae Rubra (RPR) to mice separately. Results Fructus Piperis (FP), Cortex Cinnamoni (CC), Fructus Evodiae (FE), Fructus Foeniculi (FF), and Pericarpium Zanthoxyli (PZ) compound prescription with RPR can increase the blood concentration of paeoniflorin in different degrees (P
