Determination of terpenelactones in Yinxingye Soft Capsule by HPLC-ELSD
- VernacularTitle:HPLC-ELSD法测定银杏叶软胶囊中萜类内酯的含量
- Author:
Yazhong ZHANG
;
Yaqiu ZHOU
;
Juan WANG
;
Jianshen TAO
- Publication Type:Journal Article
- Keywords:
Yinxingye Soft Capsule;
terpenelactones;
HPLC;
ELSD
- From:
Chinese Traditional Patent Medicine
1992;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To determine the content of terpenelactones in Yinxingye Soft Capsule(Folium Ginkgo). METHODS: HPLC with Evaporative Light Scattering Detector (ELSD) was established to determine the content of terpenelactones in Yinxingye Soft Capsule. The analysis was carried out on C 18 column. The mobile phase was 1-propanol-THF-water(1∶15∶84). The operating conditions of the ELSD were a nebulizer nitrogen flow-rate of 3.5L?min -1 and an evaporator tube temperature of 115℃. RESULTS: No interference was found in the terpenelactones peak position. The method was simple, with a good linear relationship. The relative standard deviation of reproducibility was 1.04% and the average recovery was 97.1%. CONCLUSION: The method can be used for quality control.
