Determination of oxymatrine and matrine in Compound Shiwei Tablets by HPLC
- VernacularTitle:HPLC同时测定复方石韦片和苦参药材中苦参碱和氧化苦参碱的含量
- Author:
Weike JIANG
;
Li WANG
- Publication Type:Journal Article
- Keywords:
oxymatrine, matrine;
HPLC;
Compound Shiwei Tablets;
Radix Sophorae Flavescentis
- From:
Chinese Traditional Patent Medicine
1992;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM:To establish an assay of oxymatrine and matrine in Compound Shiwei Tablets(Folium Pyrrosiae, Radix Sophorae Flavescentis, Radix Astragali, Herba Polygoni Avicularis, etc.) and Radix Sophorae Flavescentis by HPLC. METHODS: Diamonsil C 18 (10 ?m,250 mm?4.6 mm) analytical column was used.The mobile phase consisted of methanol-0.2% phosphoric acid solution (45∶55). The detection wavelength was 220nm. RESULTS : The average recoveries of oxymatrine and matrine in Compound Shiwei Tablets were 100.3% and 100.6% , respectively and in Radix Sophorae Flavescentis were 101.0% and 101.2%, respectlively. CONCLUSION: This method could be used for the quality evaluation of Compound Shiwei Tablets and Radix Sophorae Flavescentis.
