Intraarterial chemotherapy for bulky uterine cervical carcinoma
- VernacularTitle:巨块型宫颈癌介入化疗疗效探讨
- Author:
Yicun PANG
;
Yueqing SONG
- Publication Type:Journal Article
- Keywords:
Intraarterial chemotherapy;
Uterine cervical cancer
- From:Journal of Interventional Radiology
2001;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effects of intraarterial chemotherapy for bulky uterine cervical carcinoma. Methods One hundred untreated patients with stage Ⅰb-Ⅲa uterine cervical carcinoma were included in the study. Intraarterial chemotherapy was undertaken with a combination of Cisplatin (DDP) 50 mg/m 2 or Paraplatin 300 mg/m 2, Epiadriamycin (E-ADM)45 mg/m 2 one time/2ws. Results The overall response rate was 87.0%. Radical hysterectomy was performed in 73 patients with less bleeding and shorter operative time than those of untreated group. The major adversary effects were leukocytopenia, nausea, and vomiting. Conclusions Intraarterial chemotherapy is effective for preoperative treatment of uterive cesrvical cances with easier radical hysterectomy, especially for inoperable bulky ones.
