Effect of depside salt from salvia miltiorrhiza on angina pectoris and platelet function
- VernacularTitle:丹参多酚酸治疗心绞痛患者的临床疗效及对血小板功能的影响
- Author:
Ping YAN
;
Xinping LUO
;
Haiming SHI
- Publication Type:Journal Article
- Keywords:
Depside Salt from Salvia Miltiorrhiza;
Angina pectoris;
Platelet aggregation;
P-selectin;
Exercise electrocardiography(ECG)
- From:
Journal of Interventional Radiology
2004;0(S2):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effect of Depside Salt from Salvia Miltiorrhiza on angina pectoris and platelet function.Methods The study group was comprised of 56 patients with stable angina,who were randomly divided into the high-dosage Depside Salt from Salvia Miltiorrhiza group,the low-dosage Depside Salt from Salvia Miltiorrhiza group and the Danshen control group. Before and after the 14-day treatment,the clinical symptom and serum level of PAG, P-selectin were measured,and exercise electrocardiography was performed. Results After treatment with Depside Salt from Salvia Miltiorrhiza,the symptom of angina pectoris was alleviated and exercise ECG was improved,while no significant difference was found compared with control group.Serum PAG and P-selectin were decreased after treatment with Depside Salt from Salvia Miltiorrhiza ,and significantly more than Danshen.Conclusion Depside Salt from Salvia Miltiorrhiza injection can remarkably inhibite the aggregation and activation of platelet,and is effective for angina pectoris.
