The clinical efficacy of carvedilol on the treatment of chronic heart failure
- VernacularTitle:卡维地洛治疗慢性心力衰竭的疗效观察
- Author:
Jun KE
;
Jian ZHAO
;
Weihua LUO
- Publication Type:Journal Article
- Keywords:
Heart failure,congestive;
Carvedilol;
Effect
- From:
Journal of Interventional Radiology
2004;0(S2):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the efficacy and safety of carvedilol in patients with chronic heart failure (CHF).Methods Forty-six patients with CHF were randomly divided into carvedilol group (n=26) and control group (n=20) on the basis of standard therapy including digitalis, diuretics and ACEI. Before and after treatment, NYHA class, echocardiography and adverse reaction were observed. Results The mean dose of carvedilol was titrated to 25.14?3.05mg/day. After treatment, NYHA class was improved in both groups. Left ventricular end-diastolic diameter (LVEDD) measured by echocardiography reduced [(58.79?8.99)mm vs (64.68?10.12) mm,P