Effects of Ligu Capsules in Preventing and Treating Menopausal Osteoporosis of Rats
- VernacularTitle:力骨胶囊对绝经后骨质疏松症大鼠的影响
- Author:
Yahong ZHAO
;
Xianfeng GONG
;
Xingjun LIU
;
Minwei WANG
- Publication Type:Journal Article
- Keywords:
Osteoporosis;
Ligu capsules;
Ovariectomized rats
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
2000;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of Ligu Capsules in preventing and treating menopausal osteoporosis in ovariectomized rats.Methods Rat models with osteoporosis were established by ovariectomy. Bone mineral density of femur,dry and wet bone weight and blood biochemical parameters were measured before and after treatment.Results Compared with the model group, Ligu Capsules increased femur bone mineral density,elevated the serum levels of Ca,P,Mg ,Zn and CT, decreased serum BGP level and hydroxyproline/creatinine(Hyp/Crea)ratio,increased dry weight, wet weight and ash weight of femur, as well as the bone length, bone volume, and bone diameter.Conclusion Ligu Capsules can prevent and treat osteoporosis in ovariectomized rats.
