Expression of p57~(kip2) protein in bladder transitionalcell carcinoma and its significance
- VernacularTitle:p57~(kip2)在膀胱癌的表达及意义
- Author:
Jiabing LI
- Publication Type:Journal Article
- Keywords:
Bladder neoplasm;
Cell cycle;
p57~(kip2) protein;
PCNA
- From:
Journal of Chongqing Medical University
2003;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To assess the relation and clinical significance between p57 kip2 protein and the biological behavior of bladder transitional cell carcinoma(BTCC).Methods:The expression of p57 kip2 protein and PCNA was detected in 50 cases of BTCC,14 normal bladder mucosa by immunohistochemical method.Results:Positive rate of p57kip2 protein in BTCC was 46%,which was significant lower than 78.6% in normal bladder muscosa.( ? 2=4.660, P 0.05);positive rate of PCNA in BTCC was 60 %(30/50),which was significantly higher than 0%(0/14) in normal bladder mucosa( ? 2=15.812, P
