Expression and significance of VEGF in primary breast carcinoma tissues
- VernacularTitle:VEGF在乳腺癌组织的表达及其临床意义
- Author:
Zhijun SUN
- Publication Type:Journal Article
- Keywords:
Primary breast carcinoma;
VEGF;
Prognosis
- From:
Journal of Chongqing Medical University
2003;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the expression of VEGF in primary breast carcinoma tissues and to evaluate the predictive significance in recurrence of the primary breast carcinoma.Methods:Expression of VEGF in 63 benign and malignant breast paraffin-embedded specimens was determined and the difference in the positive rate and the intensity of positive reaction of VEGF were compared.Results:The positive rate of VEGF was significantly increased in malignant breast tissues compared with benign breast tissues.While the positive intensity of VEGF was significantly increased in tissues with recurrence of the primary breast carcinoma compared with the tissues of no recurrence of breast carcinoma and multiple breast carcinoma.Conclusion:The expression of VEGF may indicate the proliferating activity of carcinoma cell.The positive intensity of expression of VEGF may be valuable in prediction of the recurrence of primary breast carcinoma.
