Effect of TSPG on apoptosis of K562 cells and the expression of Fas,sfas
- VernacularTitle:人参总皂甙对K562细胞Fas及其可溶性受体的影响
- Author:
Weixi CAO
- Publication Type:Journal Article
- Keywords:
TSPG;
K562;
Apoptosis;
Fas;
sfas
- From:
Journal of Chongqing Medical University
2003;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:Our purpose is to clarify the mechanisms for total saponins of Panax ginseng(TSPG) inducing K562 cells to apoptosis.Methods:By using morphological observation and TUNEL,the effect of TSPG on apoptosis of K562 cells were studied.The expression of Fas was studied by immunocytochemistry,and sfas was assayed by ELISA.Results:The results indicated that 50,100?g/ml TSPG could induce K562 cells to apoptosis.Our experiment also showed after induced by TSPG,the ratio of positive K562 cells of expression Fas is increased ( P
