Clinical trial on gatifloxacin against acute exacerbation ofchronic bronchitis (AECB) in adults
- VernacularTitle:甲磺酸加替沙星氯化钠注射液与环丙沙星注射液治疗慢性支气管炎急性发作的临床疗效及安全性观察
- Author:
Aizhong ZENG
- Publication Type:Journal Article
- Keywords:
Gatifloxacin;
AECB;
Ciprofloxacin
- From:
Journal of Chongqing Medical University
2003;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the clinical efficacy and safety of gatifloxacin in the treatment of acute exacerbation of chronic bronchitis(AECB).Methods:23 patients in each group (trial or control) were treated with gatifloxacin or ciprofloxacin,respectively,for 5 to 14 days.Results:The clinical effective rates of the two groups were 91.3% and 78.3%,respectively.The bacterial eradication rates of the two groups were 91.7% and 72.7% respectively.Incidence of adverse reactions of the two groups were 12.5% and 8.7%,respectively.Conclusion:The efficacy and safty of gatifloxacin in treating AECB is reliable and superior to ciprofloxacin.
