- Author:
Oh Young BANG
1
;
Kwang Ho LEE
;
Suk Jae KIM
;
David S LIEBESKIND
Author Information
- Publication Type:Case Report
- Keywords: stroke; ischemia; perfusion; collaterals; magnetic resonance imaging
- MeSH: Diffusion; Hemorrhage; Humans; Ischemia; Magnetic Resonance Imaging; Middle Cerebral Artery; Perfusion; Reperfusion; Stroke
- From:Journal of Clinical Neurology 2010;6(1):41-45
- CountryRepublic of Korea
- Language:English
- Abstract: BACKGROUND: It has recently been suggested that diffusion and perfusion MRI can identify subgroups likely to benefit or potentially be harmed by reperfusion therapies. CASE REPORT: We investigated serial MRI data of two patients with occlusion of the proximal middle cerebral artery (MCA). In both cases, acute multiple cortical infarcts evident on diffusion-weighted imaging (DWI) and perfusion-weighted imaging (PWI) showed extensive areas of severe perfusion delays, indicating a malignant MRI profile. However, despite the malignant MRI profiles in these cases, no new ischemic lesions or hemorrhage evolved even in the presence of persistent arterial occlusion, and the patients recovered without sequelae. CONCLUSIONS: These two cases suggest that time-domain PWI findings should be interpreted with caution in certain scenarios of acute ischemic stroke.