Clinical study of hemostatic coagulation mar kers in prethrombosis state of pregnancy induced hypertension
- VernacularTitle:妊娠高血压综合征患者血浆止凝血分子标志物水平变化的意义
- Author:
Qing SHI
;
Chen CHEN
;
Xuefeng WANG
;
Hongli WANG
- Publication Type:Journal Article
- Keywords:
Pregnancy complications, cardiovascular;
H ypertension;
P-selelctin;
Antithrombins;
Biological markers
- From:Chinese Journal of Obstetrics and Gynecology
2000;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between the hemostatic coagulation markers of pr ethrombosis state and pregnancy induced hypertension(PIH). Methods Forty-five PIH patients and 20 control patients were studied. P-selectin, pro thrombin fragments 1+2 (F1+2), D-dimers(D-D) and plasmin-antiplasmin complex (PAP) were measured by enzyme linked immunosorbent assay. Antithrombin activity (AT: A) was measured by chromogenic peptide substrate assay. Results (1) The P-selectin level of pre-delivery in moderate and severe PIH patients w as (66?24)?g/L and (80?30)?g/L, it was (49?15)?g/L in the control group ( both P
