A Meta-analysis of risk factors for de1ayed cerebral vasospasm after aneurysm subarachnoid hemorrhage

VernacularTitle:动脉瘤性蛛网膜下腔出血致迟发性脑血管痉挛危险因素的Meta分析
Author: Zhengjun WU
Publication Type:Journal Article
Keywords: subarachnoid hemorrhage; delayed cerebral vasospasm; risk factors; Meta-analysis
From: Chongqing Medicine 2014;(14):1718-1720,1723
CountryChina
Language:Chinese
Abstract: Objective To systematically analyze the risk factors for de1ayed cerebral vasospasm after aneurysm subarachnoid hemorrhage in order to provide evidence for prevention and treatment of the disease .Methods Articles of risk factors for de1ayed cerebral vasospasm after aneurysm subarachnoid hemorrhage from VIP ,CBM ,CNKI ,Wangfang and pubmed ,springlink ,highwire database ,and correlated indexes were extracted for Meta‐analysis by using RevMan 5 .1 .Results Thirteen articles were selected . The heterogeneity of all data was equilibrium ,and used fixed effects model .The difference showed statistical significance in the his‐tory of hypertension ,Fisher > Ⅱ ,age>50 years and the posterior circulation aneurysm (P<0 .05) .and no statistical significance in the sex ,smoking history ,the way of treatment(P>0 .05) .The symmetry of funnel plots prompted no publication bias .Conclusion Patients with history of hypertension ,Fisher > Ⅱ ,age< 50 years and the posterior circulation aneurysm are at higher risk of de1ayed cerebral vasospasm ,strengthen close monitoring and management are crucial in these patients .