Serum leptin concentrations in patients with chronic congestive heart failure
- VernacularTitle:慢性心力衰竭患者血清瘦素水平
- Author:
Gang LI
- Publication Type:Journal Article
- Keywords:
Congestive heart failure;
Leptin;
Coronary heart disease
- From:
Journal of Chongqing Medical University
2003;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the changes of serum leptin in chronic congestive heart failure(CHF).Methods:The serum levels of leptin in 46 patients with NYHA cardiac function class Ⅰ and in 39 patients with CHF(14 in class Ⅱ,21 in class Ⅲ and 4 in class Ⅳ)were assessed by radioimmunoassay.Results:The serum contents of leptin were 11.674?6.911?g/l in NYHA class Ⅰ group,11.492?5.649 ?g/l in classⅡ group,7.763?3.321 ?g/l in class Ⅲ group,6.100? 2.657 ?g/l in class Ⅳ group and 9.018?4.519 ?g/l in CHF group.The serum levels of leptin were significantly lower in class Ⅲ group,class Ⅳ group and CHF group,compared with class Ⅰ group,respectively( t =2.185～2.786, P
