Effects of nimesulide on proliferation and apoptosis of human gastric carcinoma cells SGC-7901
- VernacularTitle:尼美舒利对人胃癌细胞株SGC-7901增殖和凋亡的影响
- Author:
Min QIAO
- Publication Type:Journal Article
- Keywords:
SGC-7901;
Nimesulide;
Apoptosis;
Proliferation
- From:
Journal of Chongqing Medical University
2003;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the effects of nimesulide on proliferation and apoptosis of human gastric carcinoma cells SGC-7901 in vitro,and provide an experimental basis for clinical application.Methods:Proliferation of human gastric carcinoma cells SGC-7901 was assessed by MTT,and apoptosis was detected by transmission electron microscope and flow cytometry.Results:Proliferation of SGC-7901 was inhibited significantly by nimesulide(range from 12.5 to 800?mol/L) in a dosage-dependant manner ( P
