A study on heart rate variability and its circadian rhythm of patients with isolated systolic hypertension
- VernacularTitle:原发性单纯收缩期高血压患者自主神经活性及其昼夜节律
- Author:
Changming DENG
- Publication Type:Journal Article
- Keywords:
Isolated systolic hypertension;
Left ventricular hypertrophy;
Heart rate variability;
Circadian rhythm
- From:
Journal of Chongqing Medical University
2003;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate heart rate variability(HRV)and its circadian rhythm of patients with isolated systolic hypertension.Methods:HRV was evaluated by using 24-hour Holter monitoring in 92 isolated systolic hypertensive patients, and compared with age-matched normal controls.Furthermore,HRV and its circadian rhythm were evaluated in two subgroups with and without left ventricular hypertrophy(LVH).Results:All HRV time domain index were lower among patients than normal controls.As compared with the patients with and without LVH,rMSSD and pNN50 were significantly decreased in patients with LVH.The circadian rhythm was blunted in patients without LVH,but it was absent in patients with LVH.Conclusion:Our results suggest that HRV is decreased in isolated systolic hypertensive patients.Parasympathetic tone is lower in patients with LVH than those without LVH,and the sympathetic/parasympathetic tone is altered.