Effects of Rhizoma Acori Tatarinowii on Amino Acids Neurotransmitter in Mice Brain
- VernacularTitle:石菖蒲对小鼠脑组织氨基酸类神经递质的影响
- Author:
Hongmei TANG
;
Ping XI
;
Min WU
;
Qingqun CAI
- Publication Type:Journal Article
- Keywords:
Rhizoma Acori tatarinowii;
Amino acid;
Neurotransmitter;
Mouse
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
2000;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effects of Rhizoma Acori Tatarinowii (RAT) on amino acids neurotransmitter in mice brain and to explore its mechanisms. Methods After treated by different parts of RAT,the cerebral contents of the amino acids neurotransmitter in rats were detected by high performance liquid chromatography (HPLC) Results Volatile oil, fluid extract and defatted decoction of RAT could significantly lower cerebral glutamic acid level. Volatile oil and fluid extract decreased the content of aspartic acid, and volatile oil could also reduce the taurine content in brain tissue. Conclusion RAT can lower the contents of excitatory amino acids(EAA ) and has protective effect on the brain.