Synergistic Immune Actions of Polysaccharides Compound
- VernacularTitle:复合多糖的免疫协同作用
- Author:
Fuqin SU
;
Hongxia CUI
;
Jicheng LIU
- Publication Type:Journal Article
- Keywords:
Polysaccharides compound;
Proliferative activity of lymphocytes;
Synergistic actions;
S180 tumor
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
2000;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the component and dose of polysaccharides compound and its inhibitive effect on the growth of S180 tumor.Methods Proliferative activity of splenolymphocytes was observed to study the component and dose of polysaccharides compound with MTT method. Mice bearing in-vivo transplanted tumor were used to evaluate the antitumor effect of polysaccharides compound.Results Polysaccharides compound, composed of lentinan100 mg/kg, agruecus blazei murill 200mg/kg and pachman 50 mg/kg,improved the activity of splenolymphocytes. Polysaccharides compound had an inhibitory effect on the growth of S180 tumor.Conclusion Polysaccharides compound with appropriate component in proper dose has synergistic immune actions and can inhibit the growth of S180 tumor.
