Analysis of the Quality of Prepared Slices of Herba Ephedrae
- VernacularTitle:麻黄饮片的质量标准研究
- Author:
Kang CHEN
;
Wenjin LIN
;
Li LIN
;
Chenchen ZHU
;
Mudan ZHANG
;
Chongyu ZHAO
- Publication Type:Journal Article
- Keywords:
Herba Ephedrae;
Quality criterion;
Ephedrine;
Pseudoephedrine;
Extract;
Ash;
Water;
Stability
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
2000;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the quality of prepared slices of Herba Ephedrae from different producing areas and to establish reference quality criterion of Herba Ephedrae.Methods Determined the content of Ephedrine and Pseudoephedrine in Herba Ephedra Prepared Herbal by HPLC.According to Chinese Pharmacopeia of 2000-year edition,extract,ash,water,impurity and foreign substance were detected; accelerated stability test was performed according to experience.Results The content of Ephedrine in Herba Ephedra is 0.995 %~1.589 %,honey-fried HerbaEphedra is 0.855 %~1.557 %;the content of Pseudoephedrine in Herba Ephedra is 0.560 %~2.087 %,honey-fried Herba Ephedra is 0.508 %~1.902 %; water-soluble extract was 8.83 %~18.30 %and 14.81%~27.45 %, alcohol-soluble extract was 7.74 %~18.83 %and 14.15 %~27.34 %, the total ash content was 6.49 %~10.29 %and 6.34 %~10.24 %and acid-insoluble ash was 0.19 %~0.42 %and 0.18 %~0.42 %in Herba Ephedrae and honey-prepared Herba Ephedrae respectively.The average water content was 8.10 %(s=0.3961)and 4.02 %(s=0.4674)and average content of impurity and foreign substance was 2.02 %(s=0.1954)and 2.01 %(s=0.2209)in Herba Ephedrae and honey-prepared Herba Ephedrae respectively.Conclusion This research will provide a reference criterion for the quality control of prepared slices of Herba Ephedrae.