Determination of Arsenic and Copper in Chinese Patent Medicines by Microwave-digestion Atomic Absorption Spectrometry
- VernacularTitle:微波消解-原子吸收分光光度法测定中成药中砷、铜的含量
- Author:
Lijuan ZHANG
;
Qun MA
;
Jing WANG
;
Xuexin GU
;
Shuyan WANG
- Publication Type:Journal Article
- Keywords:
Atomic absorption spectrometry;
Microwave digestion;
Chinese patent medicine;
Hydride generation;
Arsenic;
Copper
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
2000;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To establish a method for the determination of arsenic and copper in Chinese patent medicines.Methods Digested by microwave,the content of arsenic in Liuwei Dihuang Pill (prepared with water and honey) was measured by sequence flowing injection-hydride generation-atomic absorption spectrometry and content of copper by flame atomic absorption spectrometry. Effects of factors,including digestion temperature,smashing granularity of samples,proportion of digestive ingredients,volume of digestive agents,digestion procedure and digestion time,on the content determination were studied.Results Recoveries of arsenic and copper were 100.8%～114.3%and 94.4%～110.2%respectively under optimum conditions.Conclusion This method is simple and effective for the content determination of heavy mental in Chinese patent medicines.
