Analysis on etiology and prognosis of 223 children cases of acute kidney injury

VernacularTitle:223例儿童急性肾损伤的病因及预后分析
Author: Guochang YE ; Qiu LI ; Chao WEN
Publication Type:Journal Article
Keywords: kidney injury; acute; etiology; prognosis; child
From: Chongqing Medicine 2014;(10):1181-1183,1186
CountryChina
Language:Chinese
Abstract: Objective To investigate the etiology and prognostic factors of acute kidney injury (AKI) in pediatric patients . Methods The clinical data of children patients with AKI in this hospital ,including the clinical features ,causes and outcomes ,were retrospectively analyzed .The relationship between the risk factors and prognosis was analyzed .Results Infants were dominated by the prerenal factors and the other age groups were dominated by the renal factors .The univariate analysis revealed that the AKI stage ,etiology ,mechanical ventilation ,sepsis/septic shock ,MODS ,acidosis ,creatinine initial value ,creatinine peak value and serum potassium were the factors affecting prognosis .The Logistic regression analysis showed that mechanical ventilation ,MODS and sep-sis/septic shock were the independent risk factors affecting prognosis .Conclusion The etiology of AKI in children is diverse and its distribution has the age characteristics .Mechanical ventilation ,MODS and sepsis/septic shock are the independent risk factors af-fecting prognosis .The early diagnosis and the active treatment conduces to improve prognosis .