PROLIFERATION OF CERVICAL RESERVE CELLS AND IMMUNOHISTOCHEMICAL STUDY OF CD44v5
- VernacularTitle:子宫颈储备细胞增生与CD44v5在其细胞中的表达
- Author:
Rui ZHAO
;
Yuanli ZHU
;
Xianmei ZHOU
;
Simao YE
;
Ruoyun BAI
;
Li GENG
- Publication Type:Journal Article
- Keywords:
Cervix;
Reserve cells;
CD44v5
- From:
Acta Anatomica Sinica
2002;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective Cervical reserve cells are the maternal cells of cervical neoplasia. It's proliferation and origin were studied. Methods The pathological morphology of cervical reserve cell proliferating was observed by light microscopy in 238 cases of cervical benign diseases; Immunohistochemical technology of CD44v5 was used to inspect the expression of cervical reserve cells in 54 cases. Results and Conclusion 1.Reserve cell proliferation was common in most cases of cervical benign diseases and it was originated from stroma; 2 The proliferating reserve cells were composed of four types:large cells, small cells, clear cells and spindle cells; 3The expression of CD44v5 in reserve cells showed 100% strongly positive. The cells proliferation was common in begin diseases of cervix; Reserve cells possibly were originated from stroma.