Hemostasis of Xuehanjing Oral Liquid
- VernacularTitle:血汗净口服液的止血作用及机制
- Author:
Zhuo ZHANG
;
Ziming ZHAO
;
Shunhan XIAO
;
Dalian QIN
;
Yuxi XIONG
- Publication Type:Journal Article
- Keywords:
Xuehanjing Oral Liquid;
Auena fatua L. hemostasis;
rat;
mouse;
rabbit
- From:
Chinese Traditional Patent Medicine
1992;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To observe the hemostatic effect and hemostasis mechanism of XHJ (Auena fatua L.) oral Liqnid on animals. METHODS: Bleeding time (BT) and clotting time (CT) were measured by means of tail cutting and glass slide method on mice, Von willebrand factoe (vWF), prothrombin time (PT) and Kaolin partial thromboplastin time (KPTT) were observed by immunoterbidimerry and coagulase test, antithrombin Ⅲ(AT-Ⅲ) by chromophoric matrix method platelet count by tissue plasminogen activator (tPA), plasminogen activatore inactivator (PAI). CONCLUSION: The results indicate that XHJ has remarkable effect on hemostasis; Its mechanism is related to accelerating blood coagulatlon, inhibiting fibrinolytic activity, adding blood vessel endothelial cell release and improving platelet adhesiveness and aggregation.