Relationship Between Syndrome Patterns of Systemic Lupus Erythematosus and Soluble Adhesion Molecules
- VernacularTitle:系统性红斑狼疮辨证分型与可溶性粘附分子之间关系探讨
- Author:
Minghua ZHU
;
Zhisheng LU
;
Shujiang HUANG
;
Jiemin HONG
- Publication Type:Journal Article
- Keywords:
LUPUS ERYTHEMATOSUS, SYSTEMIC/immunology;
LUPUS ERYTHEMATOSUS, SYSTEMIC/ pathogenesis (tcm);
LIVER-KIDNEY YIN DEFICIENCY;
PREDOMINANCE OF HEAT TOXIN;
CELL ADHESION MOLECULES/blood
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
2000;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
[ Objective ] To investigate the decisive factor of syndrome differentiation of systemic lupus erythematosus (SLE) , so as to provide its experimental evidence. [Methods] Serum levels of soluble intercellular adhesion molecule-1 (sICAM-1) and soluble vascular cell adhesion molecule-1 (sVCAM-1) in SLE patients with yin deficiency of the liver and kidney (group B) and with excessive toxic heat (group C) were detected by enzyme-linked immunosorbent assay (ELISA) . Serum levels of sICAM-1 and sVCAM-1 in SLE patients were compared with those in healthy volunteers (group A). Relationship of serum C-reaction protein (CRP), complement 3 ( C3) and complement 4 (C4) with sICAM-1 and sVCAM-1 as well as relationship between sICAM-1 and sVCAM-1 in SLE patients were observed. [ Results ] Serum levels of sICAM-1 and sVCAM-1 in groups B and C were higher than those of group A ( P
