Effect of Suiqing Pill on Hepatic Carcinomatous Metastasis in Mice
- VernacularTitle:髓清丸对小鼠肝癌转移的影响
- Author:
Zhenjiang YANG
;
Xia ZHAO
;
Yingzhen ZOU
;
Xia QIU
;
Ling DAI
- Publication Type:Journal Article
- Keywords:
SUIQING PILL/therapeutic use;
HEPATIC TUMOR, EXPERIMENTAL/TCD therapy;
XENOGRAFT ANTITUMOR ASSAYS;
NEOPLASM TRANSPLANTATION/TCD therapy;
DISEASE MODELS, ANIMAL;
MICE
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
2000;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
[Objective] To investigate the effect of Suiqing Pill (SP), a Chinese prescription with the actions of activating blood and removing blood-stasis, on growth and metastasis of tumor. [Methods] Sixty C57BL/6 mice were randomized to three groups: group A (model control), group B (low-dose SP) and group C (high-dose SP). H22 hepatocarcinomatous metastasis models were established by subcutaneous injection of H22 hepatocarcinoma cells into the right lower limb. The inhibitory rate of tumor weight, incidence of metastatic carcinoma of lung, metastasis of lymph node, survival time and life-span prolongation rate were observed. [Results] The weight of tumor was reduced and the inhibitory rate of tumor weight was 36.83% in group B (P
