Study of morphological changes in levator ani muscle of patients with stress urinary incontinence or pelvic organ prolapse
- VernacularTitle:压力性尿失禁及盆底组织膨出患者肛提肌形态学的观察
- Author:
Juan CHEN
;
Jinghe LANG
;
Lan ZHU
;
Zhufeng LIU
;
Dawei SUN
;
Jinhua LENG
;
Haitao REN
;
Yanhuan ZHAO
;
Hongzhi GUAN
- Publication Type:Journal Article
- Keywords:
Urinary incontinence, stress;
Anus;
Muscle fibers
- From:
Chinese Journal of Obstetrics and Gynecology
2001;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
0. 05) . The muscular fiber density of levator ani muscles in SUI and POP groups was decreased, fibers were arranged in disorder and separated by large quantities of dense connective tissues with infiltrating inflammatory cells. The muscle fiber fascicles showed obvious grouped denervative atrophy, fiber type grouping and angular in shape. And also there was myopathic degeneration such as centrally located nuclei, peripheral phagocytosis and vacuolated necrosis. Conclusions There are both neurogenic and myopathic alterations in levator ani muscle's structure in patients with SUI and POP. The presence of both acute and chronic abnormalities indicates that the weakness of pelvic floor is a consequence of prolonged denervation.
