Changes of coagulation function and platelet-related parameters of patients with acute pancreatitis and their clinical significance
10.3969/j.issn.1673-4130.2014.10.020
- VernacularTitle:急性胰腺炎患者凝血功能、血小板相关参数的改变及其临床意义
- Author:
Yuling PAN
;
Hongwei TANG
;
Mianyang LI
;
Chengbin WANG
- Publication Type:Journal Article
- Keywords:
pancreatitis,acute;
coagulation function;
platelet-related parameters
- From:
International Journal of Laboratory Medicine
2014;(10):1280-1281,1284
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the changes of coagulation function and platelet-related parameters of patients with acute pancre-atitis(AP) and their clinical significance .Methods 36 patients with AP were served as the AP group ,38 healthy people ,the control group .Healthy people in the control group and patients in the AP group at the time of admission and remission were subjected to detection of serum amylase ,lipase ,leukocytes ,neutrophils ,lymphocytes ,platelets ,mean platelet volume(MPV) ,platelet distribution width(PDW),prothrombin time(PT),thrombin time(TT),activated partial thromboplastin time(APTT),prothrombin activity (PTA) ,international normalized ratio (INR) ,fibrinogen(FIB) and D-dimer(D-D) levels .Results Levels of serum amylase ,lipase , TT ,INR ,FIB ,and D-D of patients in AP group were significantly higher than those in the control group(P<0 .01) ,while their PT , PTA levels were significantly lower than those in the control group (P<0 .01) .Differences of leukocytes ,neutrophils ,lymphocytes and MPV of AP patients between at the time of admission and remission were statistically significant (P<0 .01) .Conclusion De-tections of coagulation function and platelet-related parameters changes of AP patients contribute to evaluation of the patients′con-dition and prognosis .
