The clinical features of serious opioid overdoses and effects of naloxone
- VernacularTitle:重症阿片类中毒及其纳洛酮抢救的疗效观察
- Author:
Xuemei CHEN
- Publication Type:Journal Article
- Keywords:
Opioid overdose;
Naloxone;
Treatment
- From:
Journal of Chongqing Medical University
1986;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the clinical features of serious opioid overdoses and effects of naloxone.Methods:32 cases of serious opioid overdose were involved.All patients were treated with naloxone,the change in consciousness and respiration,cure rate and the interval time,during which naloxone takes effect were observed.Results:Abnormal mental status,substantially decreased respiration,miotic pupils,and hypotension,even the apnea and cardiac arrest were found to be clinical characteristics.Naloxone could quickly reverse the respiratory depression,abnormal mental status,and hypotension.The cure rate was 90.6%.Conclusion:Effects of naloxone on serious opioid overdoses is confirmed,which is worthy of being widely used in clinic.
