Effect of Bony Extracts of Myospalox Fontanierii on Lymphocyte Transferring Factor and Interleukin-1
- VernacularTitle:中华鼢鼠骨提取物对淋巴细胞转移因子和白细胞介素-1的影响
- Author:
Li XU
;
Taihui FANG
;
Kui YANG
- Publication Type:Journal Article
- Keywords:
Myospalox fontanierii;
immunosuppression;
Interleukin-1;
Lymphocyte transferring factor;
Adjuvant arthritis
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
1993;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the influence of bony extracts of Myospalox fontanierii(MF)on immune function in rats with hypersensitive reactive inflammation induced by Freund's complete adjuvant(FCA).Methods Levels of lymphocyte transferring factor(TF)and interleukin-1(IL-1)were detected by immunological methods.Results Extracts of MF reduced the levels of IL-1 and TF in rats with hypersensitive reactive inflammation induced by FCA;it could also depressed the lymphocytic transformation rate.Conclusion Extracts of MF exert inhibitory effect on rats with hypersensitive reactive inflammation induced by FCA and its mechanism may be related with immunosuppressive action and the inhibition of IL-1 formation.
