Influences of Ultra-fine Crushing Method on Dissolution Rate and Decocting Rate of Water-Soluble Protein in Plastrum Testudinis
- VernacularTitle:超细粉碎对龟甲水溶性蛋白质溶出度及煎出率的影响
- Author:
Changzhou CHEN
;
Dongmei SUN
;
Ruiling ZHOU
;
Xueren CHENG
;
Songling FAN
;
Deshan NING
- Publication Type:Journal Article
- Keywords:
Carapax et plastrum testudinis;
Ultra-finecrushing method;
Water-soluble protein;
Decocting rate;
Dissolution rate
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
1993;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the effects of two crushing methods on dissolution rate and decocting rate of water-soluble protein in Plastrum Testudinis.Methods The dissolution rate of water-soluble protein was compared in Plastrum Testudinis processed by the traditional crushing method(passing 100-eyes screen,fine powder)and ultra-fine crushing method(passing 300-eye screen,ultra-fine powder);besides,orthogonal design was applied to study the process technical condition of decocting rate in Plastrum Testudinis.Results Water-soluble protein in fine powder of Plastrum Testudinis was hardly detected while the dissolution rate of water-soluble protein in ultra-fine powder was 51.2 %in 20 minutes and up to 70.5 %at 2 hours.Three influencing factors of fineness,decocting frequencies and decocting time were measured with orthogonal test.The results of variance analysis showed that fineness significantly influenced the decocting rate(P .05).Conclusion The ultra-fine powder technique is propitious to the increase of dissolution rate and decocting rate of water-soluble protein in Plastrum Testudinis.