Studies on analgesic effect and toxicity of Weifuqitong Capsule
- VernacularTitle:胃腹气痛胶囊的镇痛作用及其毒性研究
- Author:
Fanxin ZENG
;
Zongxiang LI
;
Xianzhong HAN
;
Ji NIE
- Publication Type:Journal Article
- Keywords:
Weifuqitong Capsule (WFQC);
analgesia;
toxicity
- From:
Chinese Traditional Patent Medicine
1992;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To study the analgesic effect and toxicity of Weifu qitong Capsule (Rhizoma Corydalis, cortex Magnoliae Officinalis, Radix Aucklandiae, etc.) to provide experimental data for its clinical application. METHODS: The analgesic effect of Weifu qitong Capsule was assessed by hot-plate test and writhing test, its acute and subacute toxicity studies were also conducted. RESULTS: Taking high dose of Weifu qitong Capsule, after 4.5 h (6.249 g/kg) WFQC could increase pain threshold in hot-plate test. Taking low, middle or high dose of WFQC after 2 h, WFQC could significantly extend writhing latent period and decrease writhing frequency (P
