The correlation between N-terminal pro-brain natriuretic peptide and D-dimer in coronary artery disease pa-tients with type 2 diabetes

VernacularTitle:冠心病合并2型糖尿病患者N末端脑钠肽前体和D-二聚体的相关性
Author: Gang TAN ; Hongbo LUO ; Zhe CAO ; Caijin XIONG
Publication Type:Journal Article
Keywords: Coronary artery disease; Diabetes; Atrial natriuretic factor
From: Chinese Journal of Primary Medicine and Pharmacy 2014;(10):1491-1492,1493
CountryChina
Language:Chinese
Abstract: Objective To explore the correlation between N-terminal pro-brain natriuretic peptide ( NT-porB-NP) and D-dimer in coronary artery disease patients with type 2 diabetes .Methods 50 coronary heart disease patients with type 2 diabetes were selected as the study group ,and 30 healthy subjects at the same period were select-ed as the healthy control group .The serum levels of NT-porBNP and D-dimer were detected in two groups ,and the cor-relation between NT-porBNP and D-dimer was analyzed .Results The serum D-dimer and NT-porBNP levels in the study group were significantly higher than those in the control group [(2.43 ±0.58)mg/L vs (0.26 ±0.13)mg/L, (1 487.8 ±201.5)pg/L vs (83.3 ±21.4)pg/L](t=21.34,32.12,all P<0.05).The D-dimer level was positively correlated with the NT-porBNP level (r=0.564,P<0.05).Conclusion In coronary heart disease patients with type 2 diabetes ,the serum levels of D-dimer and NT-proBNP are high and closely related .